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Normal and Pathological NRF2 Signalling in the Central Nervous System

22 Jul 2022

Abstract excerpt

The nuclear factor erythroid 2-related factor 2 (NRF2) was originally described as a master regulator of antioxidant cellular response, but in the time since, numerous important biological functions linked to cell survival, cellular detoxification, metabolism, autophagy, proteostasis, inflammation, immunity, and differentiation have been attributed to this pleiotropic transcription factor that regulates hundreds...

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PMID: 35892629
DOI: 10.3390/antiox11081426

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