Article
A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer
2020-02-12
Abstract excerpt
<h4>ABSTRACT</h4> Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To-date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic variance. Here, we complemented a classical new PC GWAS (1D) with spatial autocorrelation analysis (2D) and Hi-C maps (3D) to gain additional insight into the inherited ba...
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Identifiers and source
- Literature Corpus work
- f8b9505f-c2ed-5eb5-a715-60e54adc0322
- DOI
- 10.1101/2020.02.11.941351