Article
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
Nature genetics - 11 Dec 2011
Wu Chen, Miao Xiaoping, Huang Liming, Che Xu, Jiang Guoliang, Yu Dianke, Yang Xianghong, Cao Guangwen, Hu Zhibin, Zhou Yongjian, Zuo Chaohui, Wang Chunyou, Zhang Xianghong, Zhou Yifeng, Yu Xianjun, Dai Wanjin, Li Zhaoshen, Shen Hongbing, Liu Luming, Chen Yanling, Zhang Sheng, Wang Xiaoqi, Zhai Kan, Chang Jiang, Liu Yu, Sun Menghong, Cao Wei, Gao Jun, Ma Ying, Zheng Xiongwei, Cheung Siu Tim, Jia Yongfeng, Xu Jian, Tan Wen, Zhao Ping, Wu Tangchun, Wang Chengfeng, Lin Dongxin
Abstract excerpt
Pancreatic cancer has the lowest survival rate among human cancers, and there are no effective markers for its screening and early diagnosis. To identify genetic susceptibility markers for this cancer, we carried out a genome-wide association study on 981 individuals with pancreatic cancer (cases) and 1,991 cancer-free controls of Chinese descent using 666,141 autosomal SNPs. Promising associations were...
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