Article

Defining the multiplex probe panel for detecting mutating viruses with high clinical sensitivity

2024-04-23

Abstract excerpt

<h4>ABSTRACT</h4> Nucleic acid technology has emerged as an important diagnostic for infectious diseases, cancer, cardiovascular diseases, and other diseases. However, mismatches between the probes and targets can lead to misdiagnosis. Here we determine how many mismatches between the probe and target lead to poor clinical performance and respond by developing a rationale multiplex strategy to overcome this detec...

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Literature Corpus work: f8b8ca2e-5157-543c-a3e8-995f5e92f6ae
DOI: 10.1101/2024.04.23.587389

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