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Article

DNA microarray-based mutation discovery and genotyping.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Gresham David

Abstract excerpt

DNA microarrays provide an efficient means of identifying single-nucleotide polymorphisms (SNPs) in DNA samples and characterizing their frequencies in individual and mixed samples. We have studied the parameters that determine the sensitivity of DNA probes to SNPs and found that the melting temperature (T (m)) of the probe is the primary determinant of probe sensitivity. An isothermal-melting temperature DNA...

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PMID: 22065438
DOI: 10.1007/978-1-61779-228-1_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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