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Article

An enhanced single base extension technique for the analysis of complex viral populations.

PloS one - 16 Oct 2009

Webster Dale R, Hekele Armin G, Lauring Adam S, Fischer Kael F, Li Hao, Andino Raul, DeRisi Joseph L

Abstract excerpt

Many techniques for the study of complex populations provide either specific information on a small number of variants or general information on the entire population. Here we describe a powerful new technique for elucidating mutation frequencies at each genomic position in a complex population. This single base extension (SBE) based microarray platform was designed and optimized using poliovirus as the target...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19834618
DOI: 10.1371/journal.pone.0007453
PMCID: PMC2759544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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