Article

Interplay of Interferon signalling gene expression, DNA Methylation, and inflammatory cytokines in Sjögren’s Syndrome: a multi-omics Mendelian randomization study

2024-05-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Abnormal activation of the interferon (IFN) signalling plays a central role in the progression of Sjögren’s syndrome (SS). However, the causal relationship between IFN signalling and SS remains unclear, with complex interactions existing among genetic variants, epigenetic modifications, inflammatory cytokine levels, and the expression of IFN-associated genes. Thu...

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Literature Corpus work: f8aa6ed8-5ec1-5578-aa30-de7d27a3d0b2
DOI: 10.21203/rs.3.rs-4371628/v1

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