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Inflammatory cytokines and their potential role in Sjogren’s syndrome risk: insights from a mendelian randomization study

16 Feb 2024

Abstract excerpt

AIM: This study aimed to investigate the causal impact of inflammatory cytokines on Sjogren's Syndrome (SS) and to identify potential biomarkers for SS clinical management using Mendelian Randomization (MR). MATERIALS AND METHODS: Leveraging GWAS summary data of inflammatory cytokines and SS, we executed the first two-sample MR analysis. Genetic variants from prior GWASs associated with circulating inflammatory...

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PMID: 38365917
DOI: 10.1186/s42358-024-00354-2

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