Article

An integrative multi-omics approach in Sjögren’s Syndrome identifies novel genetic drivers with regulatory function and disease-specificity

2020-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Primary Sjögren’s syndrome (SS) is a systemic autoimmune disease characterized by lymphocytic infiltration and damage of exocrine salivary and lacrimal glands. The etiology of SS is complex with environmental triggers and genetic factors involved. By conducting an integrated multi-omics study we identified vast coordinated hypomethylation and overexpression effects, that also exhibit increased va...

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Literature Corpus work: 6b5e0215-da54-5407-91e0-4ec9e40cad68
DOI: 10.1101/2020.09.14.20192211

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