Article

High-Throughput Measurement of Metastable DNA Secondary Structures using Multiplexed Low-Yield Bisulfite Sequencing (MLB-seq)

2021-05-22

Abstract excerpt

Predicting DNA secondary structures is critical to a broad range of applications involving single-stranded DNA (ssDNA), yet remains an open problem. Existing prediction models are limited by insufficient experimental data, due to a lack of high-throughput methods to study DNA structures, in contrast to RNA structures. Here, we present a method for profiling DNA secondary structures using multiplexed low-yield bisu...

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Literature Corpus work: f893380b-3f87-5768-bfb2-4f1248edca03
DOI: 10.1101/2021.05.21.445174

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