Article

Small Single-Stranded DNA Structure Prediction

2025-09-12

Abstract excerpt

Small single-stranded DNAs (ssDNAs) shorter than 100 bases, including antisense oligonucleotides and aptamers, have been extensively studied as promising therapeutics. Their three-dimensional (3D) structures can guide development and enhance clinical potential, but obtaining these structures is often costly and time-consuming. Only a limited number of small ssDNAs have their 3D structures experimentally determined...

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Literature Corpus work: 31f91f98-cadd-5387-8bf4-a0da60592647
DOI: 10.1101/2025.09.10.675391

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