Article

The balancing act of R-loop biology: The good, the bad, and the ugly

2020-01-01

Abstract excerpt

An R-loop is a three-stranded nucleic acid structure that consists of a DNA:RNA hybrid and a displaced strand of DNA. R-loops occur frequently in genomes and have significant physiological importance. They play vital roles in regulating gene expression, DNA replication, and DNA and histone modifications. Several studies have uncovered that R-loops contribute to fundamental biological processes in various organisms...

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Literature Corpus work: f859f13a-5082-5171-8bcc-04a61c421e64
DOI: 10.1016/s0021-9258(17)49903-0

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