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Detection of misfolded proteins in neurodegenerative disease models with a highly sensitive chemiluminescence probe

2025-04-12

Abstract excerpt

Visualizing misfolded proteins would greatly facilitate early diagnosis, etiology elucidation, and therapy monitoring of neurodegeneration. Although several probes have been reported, simple and versatile detection in vivo is still challenging. We demonstrated that both generic and precise detection of misfolded proteins could be achieved with a chemiluminescence probe, ADLumin-1. For the generic aspect, ADLumin-1...

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Identifiers and source

Literature Corpus work
f85744aa-269e-547e-8f2a-2046f7e71bfc
DOI
10.1101/2025.04.12.648090
Open publication

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Detection of misfolded proteins in neurodegenerative disease models with a highly sensitive chemiluminescence probeDOI 10.1101/2025.04.12.648090
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