Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amyloid fibril polymorphism: a challenge for molecular imaging and therapy

23 Jan 2018

Abstract excerpt

The accumulation of misfolded proteins (MPs), both unique and common, for different diseases is central for many chronic degenerative diseases. In certain patients, MP accumulation is systemic (e.g. TTR amyloid), and in others, this is localized to a specific cell type (e.g. Alzheimer's disease). In neurodegenerative diseases, NDs, it is noticeable that the accumulation of MP progressively spreads throughout the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyloidosis: Diagnosis, Treatment, Outcomes
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29360284
DOI: 10.1111/joim.12732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amyloid fibril polymorphism: a challenge for molecular imaging and therapyPMID 29360284Read ↗

The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseasesSemantic proximity Read ↗

Molecular determinants of protein pathogenicity at the single-aggregate levelSemantic proximity Read ↗

An interdisciplinary approach to studying mechanistic, structural and toxic features of protein aggregates associated with neurodegenerative disordersSemantic proximity Read ↗

Perspective Insights into Disease Progression, Diagnostics, and Therapeutic Approaches in Alzheimer's Disease: A Judicious UpdateSemantic proximity Read ↗

Common Features at the Start of the Neurodegeneration CascadeSemantic proximity Read ↗

Molecular rules governing the structural polymorphism of amyloid fibrils in neurodegenerative diseasesSemantic proximity Read ↗

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid AggregatesSemantic proximity Read ↗

[Conformationally altered proteins cause neurodegenerative diseases].Semantic proximity Read ↗

Protein misfolding in Alzheimer’s and Parkinson’s disease: genetics and molecular mechanismsSemantic proximity Read ↗

Protein misfolding, aggregation and mechanism of amyloid cytotoxicity: An overview and therapeutic strategies to inhibit aggregationSemantic proximity Read ↗

Conformational studies of pathogenic expanded polyglutamine protein deposits from Huntington’s diseaseSemantic proximity Read ↗

Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.