Article

Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain

2022-03-04

Abstract excerpt

Cognitive decline is a common pathological outcome during aging, with an ill-defined cellular or molecular basis. Among the cellular changes observed with age are alterations to neuronal plasticity, changes in the glial compartment and the decline of the neurogenic niche. In the recent years, the concept of inflammaging, defined as a low-grade inflammation increasing with age, has emerged as a nexus for age-relate...

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Literature Corpus work: f84f2c9c-73e3-56f8-8972-a0e5eaa9960a
DOI: 10.1101/2022.03.01.482519

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