Article

Aryl Hydrocarbon Receptor Mediates Resistance to Endocrine Therapy in Breast Cancer Cells through PTEN/AKT Pathway

2026-04-19

Abstract excerpt

<title>Abstract</title> <p>Background Endocrine therapy is generally the primary treatment option for breast cancer patients whose tumors express estrogen receptor. However, resistance to endocrine therapy is a significant clinical challenge. While the Aryl Hydrocarbon Receptor (AhR) is well established in breast cancer development, its potential role in driving resistance to endocrine treatments remains not ful...

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Literature Corpus work: f8320967-f47a-509c-9303-91d2ca84900c
DOI: 10.21203/rs.3.rs-9103920/v1

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