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Article

Molecular mechanisms of endocrine resistance and their implication in the therapy of breast cancer.

Biochimica et biophysica acta - 1 Jan 2009

Zilli Marinella, Grassadonia Antonino, Tinari Nicola, Di Giacobbe Alessia, Gildetti Simona, Giampietro Jamara, Natoli Clara, Iacobelli Stefano

Abstract excerpt

The use of endocrine agents is a safe and effective treatment in the management of hormone-sensitive breast cancer. Unfortunately, sooner or later, tumor cells develop resistance to endocrine manipulation making useless this approach. During the last decade, new molecules and intracellular signaling pathways involved in endocrine resistance have been identified. Several studies have documented that estrogen...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18804516
DOI: 10.1016/j.bbcan.2008.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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