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Article

AhR and Cancer: From Gene Profiling to Targeted Therapy.

International journal of molecular sciences - 13 Jan 2021

Paris Anaïs, Tardif Nina, Galibert Marie-Dominique, Corre Sébastien

Abstract excerpt

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been shown to be an essential regulator of a broad spectrum of biological activities required for maintaining the body's vital functions. AhR also plays a critical role in tumorigenesis. Its role in cancer is complex, encompassing both pro- and anti-tumorigenic activities. Its level of expression and activity are specific to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33451095
DOI: 10.3390/ijms22020752
PMCID: PMC7828536

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