Article

Back to the Future? The Fallopian Tube, Precursor Escape and a Dualistic Model of High-Grade Serous Carcinogenesis

2018-10-24

Abstract excerpt

Beginning with the discovery of the BRCA ovarian cancer susceptibility genes and subsequent detailed examination of risk reduction salpingo-oophorectomy (RRSO) specimens, a new paradigm of ovarian carcinogenesis has unfolded with attention to the distal fallopian tube. The primary focus has been an early cancer in the fallopian tube which is seen in virtually all incidentally discovered high-grade serous cancers i...

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Literature Corpus work: f82a3fb2-5d22-5f1c-a6e4-d6b9a589ec7c
DOI: 10.20944/preprints201810.0416.v2

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