Article
Revisiting the pathogenesis of ovarian cancer: the central role of the fallopian tube.
Archives of gynecology and obstetrics - 1 Feb 2014
Dietl Johannes
Abstract excerpt
BACKGROUND: Among all gynecological malignancies, ovarian cancer is associated with the highest rate of mortality. Recent findings now propose a pivotal role for the fallopian tube during ovarian cancer pathogenesis. NEW INSIGHTS: Until recently, ovarian cancer was thought to derive from the ovarian surface epithelium. Nevertheless, attempts to define a precursor lesion from this tissue failed. Instead,...
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