Article
Serous carcinogenesis in the fallopian tube: a descriptive classification.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2008
Jarboe Elke, Folkins Ann, Nucci Marisa R, Kindelberger David, Drapkin Ronny, Miron Alexander, Lee Yonghee, Crum Christopher P
Abstract excerpt
The fimbria is the most common site of early serous cancer (tubal intraepithelial carcinoma or STIC) in women with BRCA mutations (BRCA+). A candidate serous cancer precursor--the p53 signature--has been found in nonneoplastic secretory cells of the fimbria, suggesting serous carcinogenesis in th...
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