Article
Fallopian tube intraluminal tumor spread from noninvasive precursor lesions: a novel metastatic route in early pelvic carcinogenesis.
The American journal of surgical pathology - 1 Aug 2013
Bijron Jonathan G, Seldenrijk Cornelis A, Zweemer Ronald P, Lange Joost G, Verheijen René H M, van Diest Paul J
Abstract excerpt
Pelvic serous carcinoma is usually advanced stage at diagnosis, indicating that abdominal spread occurs early in carcinogenesis. Recent discovery of a precursor sequence in the fallopian tube, culminating in serous tubal intraepithelial carcinoma (STIC), provides an opportunity to study early disease events. This study aims to explore novel metastatic routes in STICs. A BRCA1 mutation carrier (patient A) who...
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