Article

A diencephalic pathway for movement initiation and rescue of Parkinsonian symptoms

2018-08-18

Abstract excerpt

<h4>Summary</h4> The parafascicular nucleus (Pf) of the thalamus projects to the subthalamic nucleus (STN), a major target for deep brain stimulation (DBS) in Parkinson’s disease (PD), but the function of this projection remains unknown. Here, we used optogenetics, 3D motion capture, in vivo electrophysiology and 1-photon calcium imaging, unsupervised behavioral classification, and viral-based neuroanatomical tr...

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Literature Corpus work: f821f473-7ed7-5197-a1f8-faba1c173e4a
DOI: 10.1101/395277

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