Article

Selective activation of subthalamic nucleus output quantitatively scales movements

2022-01-22

Abstract excerpt

The subthalamic nucleus (STN), a diencephalic nucleus strongly connected with the basal ganglia, is a common target for deep brain stimulation (DBS) treatments of Parkinsonian motor symptoms. The STN is thought to suppress movement by enhancing inhibitory basal ganglia output via the indirect pathway, and disrupting STN output using DBS can restore movement in Parkinson’s patients. However, previous studies on STN...

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Literature Corpus work: 9a8c7c03-5c5d-5814-87b1-00a13d7af922
DOI: 10.1101/2022.01.19.477002

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