Article

Modulation of pedunculopontine input to the basal ganglia relieves motor symptoms in Parkinsonian mice

2024-03-12

Abstract excerpt

Locomotion, the ability to move, is driven by central pattern generators in the spinal cord. However, its initiation, selection of gait and arrest are controlled by command centers in the brain stem of which the best understood is the mesencephalic locomotor region (MLR). Stimulation of the MLR can initiate or arrest movement, but its neural projections and the neural circuits that mediate these actions are poorly...

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Literature Corpus work: 1cbcb45e-0122-5b31-8430-5d5b02d6391c
DOI: 10.1101/2024.03.06.583786

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