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Precise Lineage Tracking Using Molecular Barcodes Demonstrates Fitness Trade-offs for Ivermectin Resistance in Nematodes

2024-11-09

Abstract excerpt

A fundamental tenet of evolutionary genetics is that the direction and strength of selection on individual loci varies with the environment. Barcoded evolutionary lineage tracking is a powerful approach for high-throughput measurement of selection within experimental evolution that to date has largely been restricted to studies within microbial systems, largely because the random integration of barcodes within ani...

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Literature Corpus work
f7ec2185-69f4-5250-bfb6-905628a6e84e
DOI
10.1101/2024.11.08.622685
Open publication

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Precise Lineage Tracking Using Molecular Barcodes Demonstrates Fitness Trade-offs for Ivermectin Resistance in NematodesDOI 10.1101/2024.11.08.622685
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