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Extreme allelic heterogeneity at a <i>Caenorhabditis elegans</i> beta-tubulin locus explains natural resistance to benzimidazoles

2018-07-19

Abstract excerpt

Benzimidazoles (BZ) are essential components of the limited chemotherapeutic arsenal available to control the global burden of parasitic nematodes. The emerging threat of BZ resistance among nearly all nematode species necessitates the development of novel strategies to identify genetic and molecular mechanisms underlying this resistance. All detection of parasitic helminth resistance to BZ is focused on the genot...

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Literature Corpus work
667a1d94-4b5b-5296-b745-c3008b2d9f4a
DOI
10.1101/372623
Open publication

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Extreme allelic heterogeneity at a <i>Caenorhabditis elegans</i> beta-tubulin locus explains natural resistance to benzimidazolesDOI 10.1101/372623
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