Back to search

Article

Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements

2022-09-27

Abstract excerpt

<h4>SUMMARY</h4> Diverse inbred mouse strains are among the foremost models for biomedical research, yet genome characterization of many strains has been fundamentally lacking in comparison to human genomics research. In particular, the discovery and cataloging of structural variants is incomplete, limiting the discovery of potentially causative alleles for phenotypic variation across individuals. Here, we utiliz...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d4d8dd6b-44ce-59a2-ba0c-7f343df791fb
DOI
10.1101/2022.09.26.509577
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elementsDOI 10.1101/2022.09.26.509577
A Tandem Repeat Atlas for the Genome of Inbred Mouse Strains: A Genetic Variation ResourceSemantic proximity
Sequence-based characterization of structural variation in the mouse genome.Semantic proximity
The fine-scale architecture of structural variants in 17 mouse genomes.Semantic proximity
The Mouse Genomes Project: a repository of inbred laboratory mouse strain genomes.Semantic proximity
A Murine Database of Structural Variants Enables the Genetic Architecture of a Spontaneous Murine Lymphoma to be CharacterizedSemantic proximity
Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome.Semantic proximity
A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model.Semantic proximity
Mouse genomic variation and its effect on phenotypes and gene regulation.Semantic proximity
The rate and spectrum of new mutations in mice inferred by long-read sequencing.Semantic proximity
Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype.Semantic proximity
Polymorphic SNPs, short tandem repeats and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrainsSemantic proximity
Multiple laboratory mouse reference genomes define strain specific haplotypes and novel functional lociSemantic proximity
Select a neighboring publication to make it the new centre.