Article

Tauroursodeoxycholic acid inhibits <i>Clostridioides difficile</i> toxin induced apoptosis

2022-04-14

Abstract excerpt

C. difficile infection (CDI) is a highly inflammatory disease mediated by the production of two large toxins that weaken the intestinal epithelium and cause extensive colonic tissue damage. Antibiotic alternative therapies for CDI are urgently needed as current antibiotic regimens prolong the perturbation of the microbiota and lead to high disease recurrence rates. Inflammation is more closely correlated with CDI...

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Literature Corpus work: f7e68008-3022-5ea0-a7ea-0fce0edd9edc
DOI: 10.1101/2022.04.13.488266

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