Article

EndD mediates butyrate-dependent toxin release in <i>Clostridioides difficile</i>

2026-06-23

Abstract excerpt

Clostridioides difficile is an urgent threat to human health. Current treatments for C. difficile infections (CDIs) are antibiotics and microbiome restoration therapy (MRT) for recurrent cases. However, antibiotics contribute to antibiotic resistance and recurrent CDIs and the long-term sustainability and accessibility of MRTs remains to be determined. Since a dysbiotic gut microbiome is the primary risk factor f...

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Literature Corpus work: c2ad4cb7-51c8-5da1-9123-2598b8e90740
DOI: 10.64898/2026.06.22.733756

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