Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains.

mBio - 11 Dec 2024

Ugalde Silva Paul, Desbonnet Charlene, Rice Louis B, García-Solache Mónica

Abstract excerpt

Resistance to ampicillin and imipenem in Enterococcus faecalis is infrequent. However, the evolution of resistance can occur through prolonged antibiotic exposure during the treatment of chronic infections. In this study, we conducted a long-term evolution experiment using four genetically diverse strains of E. faecalis with varying susceptibilities to ampicillin and imipenem. Each strain was subjected to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ampicillin
Share to beta-Lactam Resistance
Share to beta-Lactams

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enterococcus faecalis

Share to Genome, Bacterial

Share to Imipenem

Share to Microbial Sensitivity Tests

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 39540731
DOI: 10.1128/mbio.02897-24
PMCID: PMC11633384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains.PMID 39540731Read ↗

Evolutionary trajectories of β-lactam resistance in <i>Enterococcus faecalis</i> strainsSemantic proximity Read ↗

Beta-lactamase dependent and independent evolutionary paths to high-level ampicillin resistance.Semantic proximity Read ↗

Genetic determinants of antibiotic resistance and the evolution of trade-offs during adaptation in a single patientSemantic proximity Read ↗

Evolution of beta-lactam resistance causes fitness reductions and several cases of collateral sensitivities in the human pathogen Haemophilus influenzae.Semantic proximity Read ↗

Antibiotics of the future are prone to resistance in Gram-negative pathogensSemantic proximity Read ↗

Phenotype and genotype alteration during adaptive evolution of Enterococcus faecalis to antimicrobials.Semantic proximity Read ↗

Evolution of high-level daptomycin resistance in Enterococcus faecium during daptomycin therapy is associated with limited mutations in the bacterial genome.Semantic proximity Read ↗

Identification of Evolutionary Trade-Offs Associated with High-Level Colistin Resistance in <i>Acinetobacter baumannii</i>Semantic proximity Read ↗

Progressive Sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of Beta-Lactam Resistance without Acquisition of Beta-Lactamase GenesSemantic proximity Read ↗

Mechanisms of antibiotic resistance in enterococciSemantic proximity Read ↗

Progressive sub-MIC Exposure of <i>Klebsiella pneumoniae</i> 43816 to Cephalothin Induces the Evolution of beta-lactam Resistance without Acquisition of beta-lactamase GenesSemantic proximity Read ↗

Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.