Article

<i>APOE</i>-<i>ε</i>4 and<i>BIN1</i>increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathology

2023-04-23

Abstract excerpt

Lewy body (LB) pathology commonly occurs in individuals with Alzheimer’s disease (AD) pathology. However, it remains unclear which genetic risk factors underlie AD pathology, LB pathology, or AD-LB co-pathology. Notably, whether APOE - ε 4 affects risk of LB pathology independently from AD pathology is controversial. We adapted criteria from the literature to classify 4,985 subjects from the National Alzheimer’s C...

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Literature Corpus work: f7c83b4f-1cf8-5578-9dda-e1dc4ef55d5a
DOI: 10.1101/2023.04.21.23288938

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