Article

Apolipoprotein E4, Amyloid, and Cognition in Alzheimer’s and Lewy Body Disease

2020-11-06

Abstract excerpt

<title>Abstract</title> <p><bold><italic>Background</italic></bold>: The role of <italic>APOE4</italic> in the risk of Alzheimer’s disease, Lewy body disease, and their mixed diseases have not been evaluated in antemortem patients. Also, the <italic>APOE4 </italic>effect on β-amyloid deposition and cognition, with consideration of both Alzheimer’s and Lewy body diseases, remains unclear. We aimed to determine the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5a810016-7853-56c8-99ac-9b590385ee7e
DOI: 10.21203/rs.3.rs-100843/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E4, Amyloid, and Cognition in Alzheimer’s and Lewy Body DiseaseDOI 10.21203/rs.3.rs-100843/v1Read

APOE-ε4 and BIN1 increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathologySemantic proximity Read

APOE4 is a Risk Factor and Potential Therapeutic Target for Alzheimer's DiseaseSemantic proximity Read

<i>APOE</i>-<i>ε</i>4 and<i>BIN1</i>increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathologySemantic proximity Read

The multifaceted roles of apolipoprotein E4 in Alzheimer’s disease pathology and potential therapeutic strategiesSemantic proximity Read

Clinical and pathological examples of Alzheimer's disease, dementia with Lewy bodies, and frontotemporal dementia.Semantic proximity Read

Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.Semantic proximity Read

The proportion of Alzheimer’s disease attributable to apolipoprotein ESemantic proximity Read

Apolipoprotein E and Alzheimer disease.Semantic proximity Read

Update on the investigation into the publication record of formerBJSMeditor-in-chief Paul McCrorySemantic proximity Read

Molecular Crossroads: Shared and Divergent Molecular Signatures in Alzheimer’s Disease and Dementia with Lewy BodiesSemantic proximity Read

Glial activation mediates phenotypic effects of<i>APOEε4</i>and sex in Alzheimer’s diseaseSemantic proximity Read

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotesSemantic proximity Read