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The human α-defensin-derived peptide HD5(1-9) inhibits cellular attachment and entry of human cytomegalovirus

2019-11-05

Abstract excerpt

<h4>ABSTRACT</h4> Human cytomegalovirus (HCMV) infection causes severe illness in newborns and immunocompromised patients. Since treatment options are limited there is an unmet need for new therapeutic approaches. Defensins are cationic peptides, produced by various human tissues, which serve as antimicrobial effectors of the immune system. Furthermore, some defensins are proteolytically cleaved, resulting in the...

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Literature Corpus work
f7afd568-d37b-58ab-9cd2-60cf7f40e419
DOI
10.1101/831594
Open publication

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The human α-defensin-derived peptide HD5(1-9) inhibits cellular attachment and entry of human cytomegalovirusDOI 10.1101/831594
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