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Recombinant expression of a new antimicrobial peptide composed of hBD-3 and hBD-4 in Escherichia coli and investigation of its activity against multidrug-resistant bacteria

2024-12-16

Abstract excerpt

<title>Abstract</title> <p>Human β-defensin(HBD), a short cationic peptide found in humans, exhibits broad-spectrum antimicrobial activity, making it a significant candidate for antimicrobial drug development. In previous studies, we fused human β-defensin 3 and human β-defensin 4 to create a chimeric human β-defensin, named H4, with enhanced antimicrobial activity and improved salt stability. However, due to the...

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Literature Corpus work
6703cd9d-495e-5d5c-acf3-5664c98b6c74
DOI
10.21203/rs.3.rs-5134762/v1
Open publication

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Recombinant expression of a new antimicrobial peptide composed of hBD-3 and hBD-4 in Escherichia coli and investigation of its activity against multidrug-resistant bacteriaDOI 10.21203/rs.3.rs-5134762/v1
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