Article

Protective Role of RIPK1 Scaffolding against HDV-Induced Hepatocyte cell death and the Significance of Cytokines in Mice

2023-10-18

Abstract excerpt

Hepatitis delta virus (HDV) infection represents the most severe form of human viral hepatitis; however, the mechanisms underlying its pathology remain incompletely understood. We recently developed an HDV mouse model by injecting adeno-associated viral vectors (AAV) containing replication-competent HBV and HDV genomes. This model replicates many features of human infection, including liver injury. Notably, the ex...

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Literature Corpus work: f79c6a97-4aee-5756-9500-30a95c82b2b6
DOI: 10.1101/2023.10.15.562448

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