Article

IFN-γ synergizes with TNF-α to induce RIPK1-independent necroptosis of mesenchymal stem/stromal cells

2024-05-14

Abstract excerpt

<title>Abstract</title> <p>Interferon gamma (IFN-γ) and tumor necrosis factor alpha (TNF-α) are two vital inflammatory factors elevated in many diseases. An inflammatory microenvironment is detrimental to residual cells, yet the precise mechanisms of cell impairment are not fully understood. IFN-γ and TNF-α have distinct effects on the immunoregulatory properties of mesenchymal stem/stromal cells (MSCs) and they...

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Literature Corpus work: ea60b468-d690-5810-a99f-392571c9d7f7
DOI: 10.21203/rs.3.rs-4368339/v1

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