Article
Dynamics of age-related catastrophic mitotic failures and recovery in yeast
2018-11-09
Abstract excerpt
Genome instability is a hallmark of aging and contributes to age-related disorders such as progeria, cancer, and Alzheimer’s disease. In particular, nuclear quality control mechanisms and cell cycle checkpoints have generally been studied in young cells and animals where they function optimally, and where genomic instability is low. Here, we use single cell imaging to study the consequences of increased genomic in...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- f747b203-84bb-53ee-9664-9e573d2bb0e8
- DOI
- 10.1101/466797