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Article

Lineage structure of the human antibody repertoire in response to influenza vaccination.

Science translational medicine - 6 Feb 2013

Jiang Ning, He Jiankui, Weinstein Joshua A, Penland Lolita, Sasaki Sanae, He Xiao-Song, Dekker Cornelia L, Zheng Nai-Ying, Huang Min, Sullivan Meghan, Wilson Patrick C, Greenberg Harry B, Davis Mark M, Fisher Daniel S, Quake Stephen R

Abstract excerpt

The human antibody repertoire is one of the most important defenses against infectious disease, and the development of vaccines has enabled the conferral of targeted protection to specific pathogens. However, there are many challenges to measuring and analyzing the immunoglobulin sequence repertoire, including that each B cell's genome encodes a distinct antibody sequence, that the antibody repertoire changes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23390249
DOI: 10.1126/scitranslmed.3004794
PMCID: PMC3699344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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