Article

Opposing roles for iron transport systems in gallium tolerance in extraintestinal pathogenic <i>Escherichia coli</i>

2025-07-01

Abstract excerpt

Gallium is a promising antibacterial candidate because it displaces iron atoms inside bacterial cells but does not undergo redox cycling. It inhibits growth by disrupting essential iron-dependent processes. However, Escherichia coli are naturally less sensitive to gallium than many other bacteria, and the mechanisms that control gallium tolerance are not completely understood. We performed a genome-wide transposo...

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Literature Corpus work: f6f000ba-1b74-5ebc-80d7-17c6869d932e
DOI: 10.1101/2025.07.01.662525

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