Article
Restoration of growth by manganese in a mutant strain of Escherichia coli lacking most known iron and manganese uptake systems.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine - 1 Jun 2016
Taudte Nadine, German Nadezhda, Zhu Yong-Guan, Grass Gregor, Rensing Christopher
Abstract excerpt
The interplay of manganese and iron homeostasis and oxidative stress in Escherichia coli can give important insights into survival of bacteria in the phagosome and under differing iron or manganese bioavailabilities. Here, we characterized a mutant strain devoid of all know iron/manganese-uptake systems relevant for growth in defined medium. Based on these results an exit strategy enabling the cell to cope with...
Topics
- Escherichia coli
- Gallium
- Iron
- Manganese
- Mutation
- Oxidative Stress
