Article
The Haemophilus influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease and development of a gallium-based screen for mutants.
Journal of bacteriology - 1 Jul 2007
Anderson Damon S, Adhikari Pratima, Weaver Katherine D, Crumbliss Alvin L, Mietzner Timothy A
Abstract excerpt
The obligate human pathogen Haemophilus influenzae utilizes a siderophore-independent (free) Fe(3+) transport system to obtain this essential element from the host iron-binding protein transferrin. The hFbpABC transporter is a binding protein-dependent ABC transporter that functions to shuttle (free) Fe(3+) through the periplasm and across the inner membrane of H. influenzae. This investigation focuses on the...
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