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Reduced glutathione levels in <i>Enterococcus faecalis</i> trigger metabolic and transcriptional compensatory adjustments during iron exposure

2025-04-10

Abstract excerpt

<h4>SUMMARY</h4> Enterococcus faecalis , a facultative anaerobic pathogen and common constituent of the gastrointestinal microbiota, must navigate varying iron levels within the host. This study explores its response to iron supplementation in a glutathione-deficient mutant strain (Δ gsh ). We examined the transcriptomic and metabolic responses of a glutathione synthetase mutant strain (Δ gsh ) exposed to iron...

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Literature Corpus work
c33d6a66-7370-59df-b762-700e458ba05d
DOI
10.1101/2025.04.04.647250
Open publication

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Reduced glutathione levels in <i>Enterococcus faecalis</i> trigger metabolic and transcriptional compensatory adjustments during iron exposureDOI 10.1101/2025.04.04.647250
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