Article
Antibacterial activity of gallium nitrate against polymyxin-resistant Klebsiella pneumoniae strains.
Diagnostic microbiology and infectious disease - 1 Feb 2022
Rossato Luana, Arantes Julia Pimentel, Ribeiro Suzana Meira, Simionatto Simone
Abstract excerpt
Iron uptake and metabolism have become attractive targets for the development of new antibacterial drugs. In this scenario, the FDA-approved iron mimetic metal gallium [Ga (III)] has been successfully researched as an antimicrobial drug. Ga (III) inhibits microbial growth by disrupting ferric iron-dependent metabolic pathways. In this study, we revealed that gallium nitrate III (GaN) inhibits the growth of a...
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