Article

Stable Flow-induced Expression of KLK10 Inhibits Endothelial Inflammation and Atherosclerosis

2021-08-10

Abstract excerpt

<h4>Introduction</h4> Atherosclerosis preferentially occurs in arterial regions exposed to disturbed blood flow ( d-flow ), while regions exposed to stable flow ( s-flow ) are protected. The proatherogenic and atheroprotective effects of d-flow and s-flow are mediated in part by the global changes in endothelial cell gene expression, which regulates endothelial dysfunction, inflammation, and atherosclerosis....

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Literature Corpus work: f680f156-9a16-5cc7-af74-f6859f332e65
DOI: 10.1101/2021.08.10.455857

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