Article
Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium.
Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2012
Fang Yun, Davies Peter F
Abstract excerpt
OBJECTIVE: Endothelial transcription factors Krüppel-like factor 4 (KLF4) and KLF2 are implicated in protection against atherogenesis. Steady-state microRNA (miR) regulation of KLFs in vivo is accessible by screening region-specific endothelial miRs and their targets. METHODS AND RESULTS: A subset of differentially expressed endothelial miRs was identified in atherosusceptible versus protected regions of normal...
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