Article

The proteomes of ovarian cancer ascitic cellular aggregates correlate with their ex vivo platinum sensitivities: a pilot study

2025-05-09

Abstract excerpt

<title>Abstract</title> <p> The accumulation of malignant ascites in the peritoneal cavity is a hallmark of advanced epithelial ovarian cancer (EOC). This fluid contains three-dimensional multicellular aggregates known as spheroids, which contribute to chemoresistance and are an accessible source of tumour material. However, many studies use spheroids generated from primary cell suspensions to reduce heterogenei...

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Literature Corpus work: f64798ec-7214-5beb-b4a9-2801cc3ff279
DOI: 10.21203/rs.3.rs-6441929/v1

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