Article
Generation of an in vitro 3D multicellular culture model of ovarian high-grade serous carcinoma
2025-11-11
Abstract excerpt
<h4>Summary</h4> The development of translational ovarian cancer models to investigate and overcome treatment resistance accounting for the impact of the tumor microenvironment is critical. Here, we present a protocol to establish a multicellular culture model that retains both genetic complexity and the microenvironment of patient tumors, is amenable for molecular and phenotypic analyses, and high throughput dru...
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Identifiers and source
- Literature Corpus work
- 60d6709b-8032-50da-85fa-3e119e07e0c8
- DOI
- 10.1101/2025.11.07.686515