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Article

Longitudinal Prediction of Drug Response in High-Grade Serous Ovarian Cancer Organoid Cultures Aligning with Clinical Responses

2024-05-14

Abstract excerpt

<h4>ABSTRACT</h4> High-grade serous ovarian cancer (HGSOC) ranks among the most aggressive gynecological malignancies. Its high mortality stems from frequent recurrence post-primary treatments and development of platinum resistance. Since, traditional drug development via animal models is time-consuming and lacks reproducibility, in precision cancer medicine, primary patient-derived organoids (PDOs) offer a solut...

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Literature Corpus work
07f3592b-c11f-5fb7-accf-d7acb25b95d9
DOI
10.1101/2024.05.09.593311
Open publication

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