Article

Assessing agreement between different polygenic risk scores in the UK Biobank

2022-02-09

Abstract excerpt

1. Polygenic risk scores (PRS) are proposed to be used in clinical and research settings for risk stratification. However, there are limited investigations on how different PRS diverge from each other for risk prediction of individuals. We compared two recently published PRS for each of three conditions, breast cancer, hypertension and dementia, to assess the stability of running these algorithms for risk predicti...

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Literature Corpus work: f6068d4c-3989-5017-98e0-8876b703a706
DOI: 10.1101/2022.02.09.22270719

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